Stefano Palmisani OS Consultant
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Dr Stefano Palmisani

Consultant in Pain Medicine and Neuromodulation



An experienced, widely published expert in chronic pain and neuromodulation, Dr Stefano Palmisani is a specialist consultant who believes in the value of collaboration within multidisciplinary teams. He is leader and an innovator, who balances his day-to-day workload with a passionate interest in research and education, with the patients in his care always remaining his number one priority.

About Dr Stefano Palmisani

After qualifying as a doctor at Sapienza University of Rome in 2005, Dr Stefano Palmisani studied anaesthesiology for four years at University Hospital Sant’Andrea, one of the headquarters of Sapienza University of Rome Medical School. He went on to enhance his knowledge of pain medicine with higher specialist training at Valencia General Hospital before adding to his expertise at Guy’s and St Thomas’ Hospital in London.

In 2011, Dr Palmisani was appointed to his current position of Consultant in Pain Medicine at Guy’s and St Thomas’ Hospital, where today he specialises in interventional pain medicine with a particular focus on minimally invasive endoscopic spine interventions, neuromodulation (alteration of nerve activity) together with clinical research. He is also a member of Guy’s and St Thomas’ Pain Department’s neuromodulation team, which is responsible for performing around 10% of all the UK’s annual neuromodulation procedures.

One of Dr Palmisani’s key initiatives has been the establishment of an endoscopic spine pain interventions service at Guy’s & St Thomas’ Hospital, where he carries out endoscopic rhizolysis treatment (nerves are intentionally heat-damaged under direct vision to prevent the relay of signals to the spine) on facet joints and sacroiliac (lower back & buttock) joints.

Currently working at London Bridge Hospital in addition to his main base at Guy’s & St Thomas’ NHS Foundation Trust, Dr Palmisani is a natural collaborator who is a firm believer in a multi-specialist approach. He plays a key role in a multidisciplinary tertiary referrals facial pain clinic tasked with treating patients with complex facial pains and headache syndromes and he is joint head of a clinic dealing with pelvic pain and urinary disorders.

Dedicated to research and education, he is the author of five journal and book chapters and has had several research articles published in peer-reviewed international journals (see


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Professional background

Dr Stefano Palmisani

Consultant in Pain Medicine and Neuromodulation

  • The International Association for the Study of Pain (IASP)
  • INS
  • The European Society of Regional Anaesthesia & Pain Therapy (ESRA)

De Blasi RA, Palmisani S, Alampi D, Mercieri M, Romano R, Collini S, Pinto
G: Microvascular dysfunction and skeletal muscle oxygenation assessed by
phase-modulation near-infrared spectroscopy in patients with septic shock.
Intensive Care Med (2005) 31: 1661- 8.
2. Stelfox HT, Palmisani S, Scurlock C, Orav EJ, Bates DW: The “To Err Is
Human Report” and The Patient Safety Literature. Qual Saf Health Care
(2006) 15: 174-178.
3. Arcioni R, Palmisani S, Della Rocca M, Romanò S, Mercieri M, De Blasi RA,
Ronconi P, Pinto G. Lateral popliteal sciatic nerve block: a single injection
targeting the tibial branch of the sciatic nerve is as effective as a doubleinjection technique. Acta Anaesthesiologica Scandinavica (2007) 51: 115-21.
4. Arcioni R, Palmisani S, Tigano S, Santorsola C, Sauli V, Romano S, Mercieri
M, Masciangelo R, De Blasi RA, Pinto G. Combined intrathecal and epidural
magnesium sulfate supplementation of spinal anesthesia to reduce
postoperative analgesic requirements: a prospective, randomized, doubleblind controlled trial in patients undergoing major orthopedic surgery. Acta
Anaesthesiol Scand (2007) 51: 482-489.
5. De Blasi RA, Palmisani S, Cigognetti L, Iasenzaniro M, Arcioni R, Mercieri M,
Pinto G. Effects of sternotomy on heart-lung interaction in patients undergoing
cardiac surgery receiving pressure-controlled mechanical ventilation. Acta
Anaesthesiol Scand (2007) 51: 441-446.
6. Palmisani S, Ronconi P, De Blasi RA, Arcioni R. Lateral or posterior popliteal
approach for sciatic nerve block: difference comes from anatomy. Anesthesia
Analgesia (2007) 105: 286.
7. Palmisani S, Arcioni R, Di Benedetto P, De Blasi RA, Mercieri M, Ronconi P.
Ropivacaine and Levobupivacaine for Bilateral Selective Ankle Block In
Patients Undergoing Hallux Valgus Repair. Acta Anaesthesiol Scand (2008)
52: 841-844.
8. De Blasi RA, Palmisani S, Boezi M, Arcioni R, Collini S, Troisi F, Pinto G.
Effects of remifentanil-based anesthesia with sevoflurane or propofol on
muscle microcirculation assessed non-invasively by near infrared
spectroscopy in adult patients undergoing maxillo-facial surgery. Br J Anaesth
(2008) 101:171-7.
9. Mercieri M, Paolini S, Mercieri A, De Blasi RA, Palmisani S, Pinto G, Arcioni
R. Tetraplegia following parathyroidectomy in two long-term haemodialysis
patients. Anaesthesia (2009) 64(9):1010-1013.
10. Bertini L, Palmisani S, Mancini S, Martini O, Ioculano R, Arcioni R. Does local
anesthetic dilution influence the clinical effectiveness of multiple-injection
axillary brachial plexus block? A prospective, double-blinded, randomized
clinical trial in patients undergoing upper limb surgery. Reg Anesth Pain Med
(2009) 34(5): 408-413.
11. De Andres J, Martorell V, Palmisani S, Villanueva V, Lopez Alarcon MD. A
double-blinded, controlled, randomized trial to evaluate the efficacy of
botulinum toxin A to treat lumbar myofascial pain in humans. Reg Anesth
Pain Med (2010) 35 (3): 255-60
12. De Andres J, Palmisani S, Asensio J, Villanueva V, Lopez Alarcon MD. Can
an Intrathecal, Catheter-Tip Associated Inflammatory Mass Reoccur? Clin J
Pain (2010) 26(7):631-4.
13. De Andres J, Tatay Vivò J, Palmisani S, Villanueva V, Minguez A. Intrathecal
granuloma formation in a patient receiving long-term spinal infusion of
tramadol. Pain Med (2010) 11(7):1059-62.
14. De Andres J, Villanueva V, Palmisani S, Cerda-Olmedo G, Lopez-Alarcon M,
Monsalve V, Minguez A, Martinez-Sanjuan V. Safety of Magnetic Resonance
Imaging in Patients with Programmable Implanted Intrathecal Drug Delivery
Systems: A 3-year Prospective Study. Anesth Analg (2011) 112 (5):1124-
15. Villanueva-Perez VL, Palmisani S, Asenzio-Samper JM, Fabregat-Cid G, De
Andres J. Spinal cord stimulation as treatment for post-herpes neuralgia
refractory to conventional therapy. Rev Neurol (2011) 53(3):190-1
16. Mercieri M, De Blasi RA, Palmisani S, Forte S, Cardelli P, Romano R, Pinto
G, Arcioni R. Changes in cerebrospinal fluid magnesium levels in patients
undergoing spinal anaesthesia for hip arthroplasty: does intravenous infusion
of magnesiu sulphate make any difference? A prospective, randomized,
controlled study. Br J Anaesth (2012) 109(2):208-15.
17. Fabregat G, Asensio-Samper J, Palmisani S, Villanueva-Perez VL, De
Andres J. Subcutaneous Botulinum Toxin for Chronic Post-Thoracotomy
Pain. Pain Pract (2013) 13(3):231-4
18. Lionetto L, Negro A, Palmisani S, Gentile G, Mercieri M, Simmaco M, Smith
T, Al-Kaisy A, Arcioni R and Martelletti P. Emerging treatment for chronic
migraine and refractory chronic migraine. Expert Opin Emerg Drugs (2012)
19. Van Buyten JP, Al-Kaisy A, Smet I, Palmisani S, Smith T. High Frequency
Spinal Cord Stimulation for the Treatment of Chronic Back Pain Patients:
Results of a Prospective Multicenter European Clinical Study.
Neuromodulation (2013) 16(1):59-65
20. Palmisani S, Al-Kaisy A, Arcioni R, Smith T, Negro A, Lambru G, Bandikatla
V, Carson E and Martelletti P. A six year restrospective review of occpital
nerve stimulation practice – controversies and challenges of an emerging
technique for treating refractory headache syndromes. J Headache Pain
(2013) 14(1):67
21. Martelletti P, Jensen RH, Antal A, Arcioni R, Brighina F, de Tommaso M,
Franzini A, Fontaine D, Heiland M, Jurgens TP, Leone M, Magis D,
Paemeleire K, Palmisani S, Paulus W, May A. Neuromodulation of chronic
headaches: position statement from the European Headache Federation. J
Headache Pain (2013) 14(1):86
22. Al-Kaisy A, Van Buyten JP, Smet I, Palmisani S, Pang D, Smith T. Sustained
effectivenes of 10 kHz high-frequency spinal cord stimulation for patients with
chronic, low back pain: 24-month results of a prospective multicenter study.
Pain Med (2014) 15(3) 347-354

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